DIU Research and Publication Archive

    • Login
    View Item 
    •   DIU Research and Publication Archive Home
    • Pharmacy
    • Project Report of B. Pharm
    • View Item
    •   DIU Research and Publication Archive Home
    • Pharmacy
    • Project Report of B. Pharm
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Comparative Study of Different Brands of Linagliptin Tablet with Innovator drug

    Thumbnail
    View/Open
    P05751.pdf (1.836Mb)
    Date
    2017-08-12
    Author
    Kamal, Sabiha
    Metadata
    Show full item record
    Abstract
    Linagliptin is a dipeptidyl peptidase 4 (DPP-4) inhibitors developed by Boehringer Ingelheim,which can be used to treat diabetes mellitus type-II. This study is done to compare the parameters (weight variation, hardness, disintegration, dissolution and assay) of film coated Linagliptin tablets. Different brands of Linagliptin tablets were collected from retail pharmacy of Bangladesh market for their evaluation test and compare with innovator drug (Trajenta). As it is an INN (International Nonproprietary Names) drug, specified method from ICH Guideline is followed for their evaluation test. The results of weight variation (±2), hardness (3.8-5.3kg/cm2), disintegration time (1.47 to 3.85 minutes), dissolution (97-106% in 0.1N HCl within 45 minutes) and assay (95-105%) tests of all marketed products comply with the Innovator drug and also with the specification. This study is done to view the scenario of the quality of different brands of Linagliptin tablets in Bangladesh market and to compare with innovator drug.
    URI
    http://hdl.handle.net/20.500.11948/1870
    Collections
    • Project Report of B. Pharm [30]

    copyright © 2002-2016  Daffodil International University. All rights reserved.
    Contact Us | Send Feedback
    Developed by 
    DIU Library IT Solution
     

     

    Browse

    All of DSpaceCommunities & CollectionsThis Collection

    My Account

    LoginRegister

    Statistics

    View Usage Statistics

    copyright © 2002-2016  Daffodil International University. All rights reserved.
    Contact Us | Send Feedback
    Developed by 
    DIU Library IT Solution